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Article

Members 6B and 14 of the TNF receptor superfamily in multiple sclerosis predisposition.

Genes and immunity - 1 Mar 2011

Blanco-Kelly F, Alvarez-Lafuente R, Alcina A, Abad-Grau M M, de Las Heras V, Lucas M, de la Concha E G, Fernández O, Arroyo R, Matesanz F, Urcelay E

Abstract excerpt

TNFRSF6B and TNFRSF14 genes were recently associated with Crohn's disease and rheumatoid arthritis. TNFRSF14 is known as herpes virus entry mediator (HVEM), and herpes viruses have been involved in the aetiology of multiple sclerosis (MS). MS patients present human herpes virus 6 (HHV6) in active plaques and increased antibody responses to HHV6. We aimed to ascertain the role of these genes in MS susceptibility...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20962851
DOI: 10.1038/gene.2010.42

Genes

TNFRSF14
TNFRSF6B
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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