Article
Synthetic lethal approaches to breast cancer therapy.
Nature reviews. Clinical oncology - 1 Dec 2010
Rehman Farah L, Lord Christopher J, Ashworth Alan
Abstract excerpt
The promise of personalized therapy for breast cancer is that therapeutic efficacy will be increased while toxic effects are reduced to a minimum. To achieve this goal, there is now an emphasis on the design of therapies that are based not only on the clinical manifestations of the disease, but also on the underlying molecular and cellular biology of cancer. However, identifying targets for personalized therapies...
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