Article
DcR3 gene polymorphisms are associated with sporadic breast infiltrating ductal carcinoma in Northeast Chinese women.
Oncotarget - 6 Sept 2016
Fu Zhenkun, Chen Shuang, Liu Shengwei, Han Shaoli, Gao Xiang, Li Dalin, Li Dianjun
Abstract excerpt
Decoy Receptor 3 (DcR3), also called TNFRSF6β, is a member of the tumor necrosis factor receptor superfamily and is a soluble receptor for FasL. DcR3 is overexpressed in cancers and contributes to tumorigenesis through immune suppression and promotion of angiogenesis. We found that DcR3 is overexpressed in breast infiltrating ductal carcinoma (IDC) cells as compared with normal controls. We also conducted a...
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