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Article

Association of TNFRSF1A and IFNLR1 Gene Polymorphisms with the Risk of Developing Breast Cancer and Clinical Pathologic Features.

Biochemical genetics - 1 Oct 2021

Hausmann Leili Daiane, de Almeida Bibiana Sgorla, de Souza Ilíada Rainha, Drehmer Manuela Nunes, Fernandes Braulio Leal, Wilkens Renato Salerno, Vieira Daniella Serafin Couto, Lofgren Sara Emelie, Lindenau Juliana Dal-Ri, de Toledo E Silva Guilherme, Muniz Yara Costa Netto

Abstract excerpt

Several genes have been associated with breast cancer (BC) susceptibility. The tumor necrosis factor receptor superfamily, member 1A (TNFRSF1A), and interferon lambda receptor 1 (IFNLR1) genes encode receptors that mediate the action of inflammatory cytokines. Previous studies have demonstrated the association of the variants rs1800693 (TNFRSF1A) and rs4649203 (IFNLR1) with some inflammatory diseases. The present...

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PMID: 33751344
DOI: 10.1007/s10528-021-10060-z

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