Article
Bilirubin and UGT1A1*28 are not associated with lower risk for ischemic stroke in a prospective nested case-referent setting.
Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2010
Ekblom Kim, Marklund Stefan L, Johansson Lars, Osterman Pia, Hallmans Göran, Weinehall Lars, Wiklund Per-Gunnar, Hultdin Johan
Abstract excerpt
BACKGROUND: Bilirubin, an antioxidant, has been associated with reduced cardiovascular disease risk. A major cause of elevated plasma bilirubin is the common UGT1A1*28 promoter polymorphism in the gene of the bilirubin-conjugating enzyme UDP-glucuronosyltransferase 1A1, which reduces transcriptio...
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