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Article

Cruciferae interact with the UGT1A1*28 polymorphism to determine serum bilirubin levels in humans.

The Journal of nutrition - 1 May 2005

Peterson Sabrina, Bigler Jeannette, Horner Neilann K, Potter John D, Lampe Johanna W

Abstract excerpt

UDP-glucuronosyltransferase (UGT) 1A1 is a conjugating biotransformation enzyme that plays a role in maintaining levels of endogenous compounds (e.g., bilirubin) and handling exogenous compounds, including carcinogens. The UGT1A1*28 polymorphism results in decreased UGT1A1 promoter activity due t...

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Identifiers

PMID: 15867280
DOI: 10.1093/jn/135.5.1051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15867280-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Cruciferae interact with the UGT1A1*28 polymorphism to determine serum bilirubin levels in humans.PMID 15867280Read ↗

UGT1A1 polymorphism is associated with serum bilirubin concentrations in a randomized, controlled, fruit and vegetable feeding trial.Semantic proximity Read ↗

Citrus fruit intake is associated with lower serum bilirubin concentration among women with the UGT1A1*28 polymorphism.Semantic proximity Read ↗

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Association between the UGT1A1*28 allele, bilirubin levels, and coronary heart disease in the Framingham Heart Study.Semantic proximity Read ↗

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UDP-glucuronosyltransferase (UGT1A1*28 and UGT1A6*2) polymorphisms in Caucasians and AsiansSemantic proximity Read ↗

CYP1A2, GSTM1, and GSTT1 polymorphisms and diet effects on CYP1A2 activity in a crossover feeding trial.Semantic proximity Read ↗

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Modulation of human serum glutathione S-transferase A1/2 concentration by cruciferous vegetables in a controlled feeding study is influenced by GSTM1 and GSTT1 genotypes.Semantic proximity Read ↗

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