Article
The structure of the talin/integrin complex at a lipid bilayer: an NMR and MD simulation study.
Structure (London, England : 1993) - 13 Oct 2010
Kalli Antreas C, Wegener Kate L, Goult Benjamin T, Anthis Nicholas J, Campbell Iain D, Sansom Mark S P
Abstract excerpt
Integrins are cell surface receptors crucial for cell migration and adhesion. They are activated by interactions of the talin head domain with the membrane surface and the integrin β cytoplasmic tail. Here, we use coarse-grained molecular dynamic simulations and nuclear magnetic resonance spectro...
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