Article
Partial support for ZNF804A genotype-dependent alterations in prefrontal connectivity.
Human brain mapping - 1 Feb 2013
Paulus Frieder M, Krach Sören, Bedenbender Johannes, Pyka Martin, Sommer Jens, Krug Axel, Knake Susanne, Nöthen Markus M, Witt Stephanie H, Rietschel Marcella, Kircher Tilo, Jansen Andreas
Abstract excerpt
Genome-wide association studies identified the single nucleotide polymorphism rs1344706 in ZNF804A as a common risk-variant for schizophrenia and bipolar disorder. Whereas the molecular function of ZNF804A is yet unclear, recent imaging genetics studies have started to characterize the neural systems architecture linking rs1344706 genotype to psychosis. Carring rs1344706 risk-alleles was associated with a...
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