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Article

Differential gene expression activity among species-specific polypyrimidine/polypurine motifs in mu opioid receptor gene promoters.

Gene - 15 Jan 2011

Choe Chung-Youl, Dong Jinping, Law Ping-Yee, Loh Horace H

Abstract excerpt

The mu opioid receptor (MOR) is the principle molecular target of opioid analgesics. An appropriate understanding of MOR gene expression across species is critical for understanding its analgesic functions in humans. Here, we undertake a cross-species analysis of the polymorphic polypyrimidine/polypurine (PPy/u) motif, a key enhancer of MOR gene expression. The mouse PPy/u motif is highly homologous to those of...

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Identifiers

PMID: 20946943
DOI: 10.1016/j.gene.2010.10.004
PMCID: PMC3009460

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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