Article
[Pyrosequencing in uro-oncology: applications in prostate cancer].
Der Urologe. Ausg. A - 1 Nov 2010
Stadler T C, Jung A, Schlenker B, Nuhn P, Ellinger J, Kirchner T, Stief C G, Bastian P J
Abstract excerpt
Changes in the methylation pattern in particular gene promoters as well as genetic sequence mutations play an important role in carcinogenesis. Molecular methods like pyrosequencing provide the specific analysis of these epigenetic and genetic modifications. In this review the relevance of these alterations for prostate cancer and the function of pyrosequencing will be described and explained on the basis of a...
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