Article
Identification of specific DNA methylation sites on the Y-chromosome as biomarker in prostate cancer.
Oncotarget - 1 Dec 2015
Yao Lushuai, Ren Shancheng, Zhang Minjie, Du Fengxia, Zhu Yasheng, Yu Hui, Zhang Chenyu, Li Xiaohua, Yang Caiyun, Liu Huixian, Wang Dong, Meng Hao, Chang Shuang, Han Xiao, Sun Yinghao, Sun Yingli
Abstract excerpt
As a diagnostic biomarker, prostate special antigen (PSA) tests always generate false positive results and lead to unnecessary and/or repeat biopsies. Therefore, there is an urgent need for developing more sensitive, specific diagnostic biomarkers. We epigenotyped methylated sites in cancer tissues and adjacent normal tissues from 66 patients. In comparison with normal adjacent tissues, we observed that there...
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