Population Studies of Methicillin-Resistant and -Sensitive <i>Staphylococcus aureus</i> Strains Reveal a Lack of Variability in the <i>agrD</i> Gene, Encoding a Staphylococcal Autoinducer Peptide

Abstract excerpt

The virulence of Staphylococcus aureus is controlled by the accessory gene regulator (agr) system, including an extracellular inducer encoded by agrD. Variable agr PCR restriction fragment length polymorphism (RFLP) patterns of unique S. aureus strains (n = 192) were determined for a region comprising agrD and parts of the neighboring agrC and agrB genes. Twelve unique RFLP patterns were identified among S....

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