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Article

Statistical analysis strategies for association studies involving rare variants.

Nature reviews. Genetics - 1 Nov 2010

Bansal Vikas, Libiger Ondrej, Torkamani Ali, Schork Nicholas J

Abstract excerpt

The limitations of genome-wide association (GWA) studies that focus on the phenotypic influence of common genetic variants have motivated human geneticists to consider the contribution of rare variants to phenotypic expression. The increasing availability of high-throughput sequencing technologies has enabled studies of rare variants but these methods will not be sufficient for their success as appropriate...

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PMID: 20940738
DOI: 10.1038/nrg2867
PMCID: PMC3743540

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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