Neurochemistry changes associated with mutations in familial Parkinson's disease.

Abstract excerpt

Parkinson's disease (PD), a common neurodegenerative disease, is characterized by the progressive loss of dopamine neurons and the accumulation of Lewy bodies and neurites. The exact role of genetic and environmental factors in the pathogenesis of PD has frequently been debated. The association of MPTP (methyl-4-phenyl-1, 2, 3, 6- tetrahydropyridine) and toxins (such as rotenone) with parkinsonism highlights the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to PINK1 gene
• Share to UCHL1 gene
• Share to Mutation