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Article

MPTP: insights into parkinsonian neurodegeneration.

Neurotoxicology and teratology - 1 Jan 2000

Speciale Samuel G

Abstract excerpt

MPTP burst upon the medical landscape two decades ago, first as a mysterious parkinsonian epidemic, triggering an unparalleled quest for the toxin's identity, and closely followed by an intense pursuit of its cellular mechanisms of action. MPTP treatment created an animal model of many features of Parkinson's disease (PD), used primarily in primates and later in mice. The critical role of oxidative stress damage...

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Identifiers

PMID: 12200192
DOI: 10.1016/s0892-0362(02)00222-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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