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Article

Dopamine turnover increases in asymptomatic LRRK2 mutations carriers.

Movement disorders : official journal of the Movement Disorder Society - 15 Dec 2010

Sossi Vesna, de la Fuente-Fernández Raul, Nandhagopal Ramachandiran, Schulzer Michael, McKenzie Jessamyn, Ruth Thomas J, Aasly Jan O, Farrer Matthew J, Wszolek Zbigniew K, Stoessl Jon A

Abstract excerpt

Increase in dopamine (DA) turnover was found to occur early in symptomatic Parkinson's disease (PD) and to be functionally related to the dopamine transporter (DAT). The objectives of this study were to examine changes in DA turnover in the asymptomatic PD phase; to compare them with changes in o...

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Identifiers

PMID: 20939082
DOI: 10.1002/mds.23356

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20939082-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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