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Article

Id genes are essential for early heart formation.

Genes & development - 1 Jul 2017

Cunningham Thomas J, Yu Michael S, McKeithan Wesley L, Spiering Sean, Carrette Florent, Huang Chun-Teng, Bushway Paul J, Tierney Matthew, Albini Sonia, Giacca Mauro, Mano Miguel, Puri Pier Lorenzo, Sacco Alessandra, Ruiz-Lozano Pilar, Riou Jean-Francois, Umbhauer Muriel, Duester Gregg, Mercola Mark, Colas Alexandre R

Abstract excerpt

Deciphering the fundamental mechanisms controlling cardiac specification is critical for our understanding of how heart formation is initiated during embryonic development and for applying stem cell biology to regenerative medicine and disease modeling. Using systematic and unbiased functional screening approaches, we discovered that the Id family of helix-loop-helix proteins is both necessary and sufficient to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28794185
DOI: 10.1101/gad.300400.117
PMCID: PMC5580654

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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