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Article

Are SNP-Smoking Association Studies Needed in Controls? DNA Repair Gene Polymorphisms and Smoking Intensity.

PloS one - 1 Jan 2015

Verde Zoraida, Reinoso Luis, Chicharro Luis Miguel, Resano Pilar, Sánchez-Hernández Ignacio, Rodríguez González-Moro Jose Miguel, Bandrés Fernando, Gómez-Gallego Félix, Santiago Catalina

Abstract excerpt

Variations in tobacco-related cancers, incidence and prevalence reflect differences in tobacco consumption in addition to genetic factors. Besides, genes related to lung cancer risk could be related to smoking behavior. Polymorphisms altering DNA repair capacity may lead to synergistic effects with tobacco carcinogen-induced lung cancer risk. Common problems in genetic association studies, such as presence of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26017978
DOI: 10.1371/journal.pone.0129374
PMCID: PMC4446361

Genes

KLC3
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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