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Article

The mouse ascending: perspectives for human-disease models.

Nature cell biology - 1 Sept 2007

Rosenthal Nadia, Brown Steve

Abstract excerpt

The laboratory mouse is widely considered the model organism of choice for studying the diseases of humans, with whom they share 99% of their genes. A distinguished history of mouse genetic experimentation has been further advanced by the development of powerful new tools to manipulate the mouse genome. The recent launch of several international initiatives to analyse the function of all mouse genes through...

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PMID: 17762889
DOI: 10.1038/ncb437

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