Article
Enigmatic origin of hepatitis B virus: an ancient travelling companion or a recent encounter?
World journal of gastroenterology - 28 Jun 2014
Zehender Gianguglielmo, Ebranati Erika, Gabanelli Elena, Sorrentino Chiara, Lo Presti Alessandra, Tanzi Elisabetta, Ciccozzi Massimo, Galli Massimo
Abstract excerpt
Hepatitis B virus (HBV) is the leading cause of liver disease and infects an estimated 240 million people worldwide. It is characterised by a high degree of genetic heterogeneity because of the use of a reverse transcriptase during viral replication. The ten genotypes (A-J) that have been described so far further segregate into a number of subgenotypes which have distinct ethno-geographic distribution. Genotypes...
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