Article
[Val384Asp in hMLH1 gene in Chinese, Japanese and German and its etiological role in colorectal cancer].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 10 Oct 1998
Wang Y, Friedl W, Propping P, Li J, Li Z, Wang J
Abstract excerpt
OBJECTIVE: To investigate Va1384Asp of hMLH1 gene in Chinese, Japanese and German after the missense mutation were identified in Chinese colorectal cancer patients and to inquire into the etiological role of this mutation in colorectal cancer. METHODS: Genomic DNA extracted from normal colon tiss...
Topics
- Adaptor Proteins, Signal Transducing
- Adult
- Aged
- Asian People
- Carrier Proteins
- China
- Colorectal Neoplasms
- Female
- Germany
- Humans
- Japan
- Male
- Middle Aged
- MutL Protein Homolog 1
- Mutation
- Neoplasm Proteins
- Nuclear Proteins
- Polymorphism, Genetic