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Article

Disrupted activity in the hippocampal-accumbens circuit of type III neuregulin 1 mutant mice.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jan 2011

Nason Malcolm W, Adhikari Avishek, Bozinoski Marjan, Gordon Joshua A, Role Lorna W

Abstract excerpt

Neuregulin 1 (Nrg1), a schizophrenia susceptibility gene, is involved in fundamental aspects of neurodevelopment. Mice lacking any one of the several isoforms of Nrg1 have a variety of schizophrenia-related phenotypes, including deficits in working memory and sensorimotor gating, loss of spines in pyramidal neurons in the ventral subiculum, loss of dendrites in cortical pyramidal cells, loss of...

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Identifiers

PMID: 20927045
DOI: 10.1038/npp.2010.180
PMCID: PMC3005939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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