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Article

Development of HLA-B*57:01 Genotyping Real-Time PCR with Optimized Hydrolysis Probe Design.

The Journal of molecular diagnostics : JMD - 1 Sept 2017

Jung Hou-Sung, Tsongalis Gregory J, Lefferts Joel A

Abstract excerpt

HLA-B*57:01 genotyping before abacavir (ABC) administration is a standard of care to avoid ABC-driven hypersensitivity reactions. Several HLA-B*57:01 tests have been developed, each with advantages and disadvantages. Some have limited accuracy, require special instrumentation, and/or are labor intensive and expensive. We developed a novel hydrolysis probe-based real-time PCR method of HLA-B*57:01 genotyping....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28732216
DOI: 10.1016/j.jmoldx.2017.05.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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