Article
Nutritional requirements of wild-type and folate transport-deficient Leishmania donovani for pterins and folates.
Molecular and biochemical parasitology - 1 Dec 1990
Beck J T, Ullman B
Abstract excerpt
The nutritional requirements for folates and pterins were assessed for two strains of Leishmania donovani promastigotes, a wild-type (D1700) parental strain and a mutant derivative (MTXA5) which possesses a markedly diminished capacity to transport both [3H]folate and [3H]methotrexate (MTX). Both...
Topics
- Affinity Labels
- Animals
- Biological Transport
- Biopterins
- Folic Acid
- Kinetics
- Leishmania donovani
- Methotrexate
- Neopterin
- Phenotype
- Pterins