Article
An additional type of male sterility and inherited urinary obstruction in mice with the t-haplotype th7.
Genetical research - 1 Jun 1996
Lyon M F
Abstract excerpt
The t-complex on mouse chromosome 17 results in transmission ratio distortion in males heterozygous for complete haplotypes, and sterility in those homozygous for semi-lethal or doubly heterozygous for complementing lethal haplotypes. This sterility is due to inability of spermatozoa to fertilize. The haplotype th7 is an unusual laboratory-derived haplotype, postulated to carry a small duplication of t chromatin....
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