Article
Identification of a cryptic lethal mutation in the mouse t(w73) haplotype.
Genetical research - 1 Dec 2004
Howell Gareth R, Bergstrom Rebecca A, Munroe Robert J, Masse Jessica, Schimenti John C
Abstract excerpt
t haplotypes are naturally occurring, variant forms of the t complex on mouse chromosome 17, characterized by the presence of four inversions with respect to wild-type. They harbour mutations causing male sterility, male transmission ratio distortion (TRD) and embryonic lethality. Mice carrying t haplotypes have been found throughout the world, and genetic studies of the lethal mutations have identified at least...
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