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Article

Metabolic consequences of sepsis-induced acute lung injury revealed by plasma ¹H-nuclear magnetic resonance quantitative metabolomics and computational analysis.

American journal of physiology. Lung cellular and molecular physiology - 1 Jan 2011

Stringer Kathleen A, Serkova Natalie J, Karnovsky Alla, Guire Kenneth, Paine Robert, Standiford Theodore J

Abstract excerpt

Metabolomics is an emerging component of systems biology that may be a viable strategy for the identification and validation of physiologically relevant biomarkers. Nuclear magnetic resonance (NMR) spectroscopy allows for establishing quantitative data sets for multiple endogenous metabolites without preconception. Sepsis-induced acute lung injury (ALI) is a complex and serious illness associated with high...

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Identifiers

PMID: 20889676
DOI: 10.1152/ajplung.00231.2010
PMCID: PMC3023293

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Source receipt: pubmed, retrieved 7 Sept 2026.

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