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Article

Multidimensional Landscape of SA-AKI Revealed by Integrated Proteomics and Metabolomics Analysis

30 Aug 2023

Abstract excerpt

Sepsis-associated acute kidney injury (SA-AKI) is a severe and life-threatening condition with high morbidity and mortality among emergency patients, and it poses a significant risk of chronic renal failure. Clinical treatments for SA-AKI remain reactive and non-specific, lacking effective diagnostic biomarkers or treatment targets. In this study, we established an SA-AKI mouse model using lipopolysaccharide...

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PMID: 37759729
DOI: 10.3390/biom13091329

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