Article
A metabolomic approach for diagnosis of experimental sepsis.
Intensive care medicine - 1 Dec 2011
Izquierdo-García José L, Nin Nicolás, Ruíz-Cabello Jesús, Rojas Yeny, de Paula Marta, López-Cuenca Sonia, Morales Luis, Martínez-Caro Leticia, Fernández-Segoviano Pilar, Esteban Andrés, Lorente José A
Abstract excerpt
BACKGROUND: The search for reliable diagnostic biomarkers of sepsis remains necessary. Assessment of global metabolic profiling using quantitative nuclear magnetic resonance (NMR)-based metabolomics offers an attractive modern methodology for fast and comprehensive determination of multiple circulating metabolites and for defining the metabolic phenotype of sepsis. OBJECTIVE: To develop a novel NMR-based...
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