Article
Polymorphisms in MTHFR and MTRR genes associated with blood plasma homocysteine concentration and sperm counts.
Fertility and sterility - 1 Feb 2011
Montjean Debbie, Benkhalifa Moncef, Dessolle Lionel, Cohen-Bacrie Paul, Belloc Stéphanie, Siffroi Jean-Pierre, Ravel Célia, Bashamboo Anu, McElreavey Kenneth
Abstract excerpt
OBJECTIVE: To investigate the relationship between MTHFR and MTRR genetic variants with respect to both blood plasma homocysteine concentration and sperm counts. DESIGN: Polymerase chain reaction followed by specific enzymatic digestion to determine the genotype of the individuals and blood plasma homocysteine quantification by high-performance liquid chromatography. SETTING: Research laboratory. PATIENT(S): Two...
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