Article
Relationship between genetic polymorphisms of methylenetetrahydrofolate reductase (C677T, A1298C, and G1793A) as risk factors for idiopathic male infertility.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Mar 2011
Safarinejad Mohammad Reza, Shafiei Nayyer, Safarinejad Shiva
Abstract excerpt
OBJECTIVE: The human methylenetetrahydrofolate reductase (MTHFR) gene plays a crucial role in folate metabolism. Data regarding the influence of MTHFR gene polymorphisms on male fertility status are scarce and conflicting. We determined associations between 3 MTHFR gene polymorphisms (C677T, A129...
Topics
- Case-Control Studies
- DNA
- Folic Acid
- Genotype
- Homocysteine
- Humans
- Infertility, Male
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Polymerase Chain Reaction
- Polymorphism, Single Nucleotide
- Semen