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Article

Pathogenetic mechanisms in radiation fibrosis.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Oct 2010

Yarnold John, Brotons Marie-Catherine Vozenin

Abstract excerpt

Deregulation of normal regenerative responses to physical, chemical and biological toxins in susceptible individuals leads to abnormal remodelling of extracellular matrix with pathological fibrosis. Processes deregulated after radiotherapy have much in common with processes associated with fibrotic diseases affecting the heart, skin, lungs, kidneys, gastro-intestinal tract and liver. Among the secreted factors...

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Source

Identifiers

PMID: 20888056
DOI: 10.1016/j.radonc.2010.09.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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