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Article

Role of TGF Beta and PPAR Alpha Signaling Pathways in Radiation Response of Locally Exposed Heart: Integrated Global Transcriptomics and Proteomics Analysis

2 Nov 2016

Abstract excerpt

Epidemiological data from patients undergoing radiotherapy for thoracic tumors clearly show the damaging effect of ionizing radiation on cardiovascular system. The long-term impairment of heart function and structure after local high-dose irradiation is associated with systemic inflammatory response, contraction impairment, microvascular damage, and cardiac fibrosis. The goal of the present study was to...

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Share to Cancer, Hypoxia, and Metabolism
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Share to Effects of Radiation Exposure

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Identifiers

PMID: 27805817
DOI: 10.1021/acs.jproteome.6b00795

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