Article
HIV‐exposed seronegative commercial sex workers show a quiescent phenotype in the CD4+ T cell compartment and reduced expression of HIV‐dependent host factors.
The Journal of infectious diseases - 1 Nov 2010
McLaren Paul J, Ball T Blake, Wachihi Charles, Jaoko Walter, Kelvin David J, Danesh Ali, Kimani Joshua, Plummer Francis A, Fowke Keith R
Abstract excerpt
Studies of human immunodeficiency virus (HIV)-exposed seronegative individuals are crucial to inform vaccine design. In the present study we demonstrated that HIV-exposed seronegative commercial sex workers produce lower levels of proinflammatory cytokines at baseline than HIV-negative control subjects. We also showed that CD4+ T cells of HIV-exposed seronegative commercial sex workers have a characteristically...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
