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Article

Reduced cellular susceptibility to in vitro HIV infection is associated with CD4+ T cell quiescence.

PloS one - 1 Jan 2012

Card Catherine M, Rutherford W John, Ramdahin Suzie, Yao Xiaojian, Kimani Makobu, Wachihi Charles, Kimani Joshua, Plummer Francis A, Ball T Blake, Fowke Keith R

Abstract excerpt

BACKGROUND: HIV preferentially establishes productive infection in activated CD4+ T cells. Since proportions of activated CD4+ T cells vary between individuals, this study aimed to determine if individuals with a greater proportion of activated CD4+ T cells would be more susceptible to in vitro HIV infection. METHODOLOGY/PRINCIPAL FINDINGS: Unstimulated peripheral blood mononuclear cells (PBMC) from various...

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Share to CD4-Positive T-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to T-Lymphocytes, Regulatory

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Source

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Identifiers

PMID: 23029309
DOI: 10.1371/journal.pone.0045911
PMCID: PMC3448692

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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