Article
HIV controllers maintain a population of highly efficient Th1 effector cells in contrast to patients treated in the long term.
Journal of virology - 1 Oct 2012
Vingert Benoît, Benati Daniela, Lambotte Olivier, de Truchis Pierre, Slama Laurence, Jeannin Patricia, Galperin Moran, Perez-Patrigeon Santiago, Boufassa Faroudy, Kwok William W, Lemaître Fabrice, Delfraissy Jean-François, Thèze Jacques, Chakrabarti Lisa A
Abstract excerpt
HIV controllers are rare individuals who spontaneously control HIV replication in the absence of antiretroviral therapy. To identify parameters of the CD4 response that may contribute to viral control rather than merely reflect a persistently low viremia, we compared the T helper profiles in two groups of patients with more than 10 years of viral suppression: HIV controllers from the Agence Nationale de Recherche...
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