Article

Trained Immunity in People Living with HIV

2025-12-23

Abstract excerpt

<h4>Background: </h4> Trained immunity (TRIM) enhances innate immune responses through epigenetic and metabolic reprogramming but can become maladaptive, contributing to chronic inflammation. In people living with HIV (PLWH), maladaptive TRIM has been proposed but remains insufficiently defined. <h4>Methods:</h4> We examined inflammatory cytokine production in monocyte-derived macrophages (MDMs) obtained from PLWH...

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Literature Corpus work: fa86d3d3-f6c8-5f68-91a3-7cebfdc21e65
DOI: 10.20944/preprints202512.2116.v1

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