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Analysis of Human Immunodeficiency Virus Type 1 Gene Expression in Latently Infected Resting CD4 <sup>+</sup> T Lymphocytes In Vivo

13 Jun 2003

Abstract excerpt

In individuals with human immunodeficiency virus type 1 (HIV-1) infection, a small reservoir of resting memory CD4(+) T lymphocytes carrying latent, integrated provirus persists even in patients treated for prolonged periods with highly active antiretroviral therapy (HAART). This reservoir greatly complicates the prospects for eradicating HIV-1 infection with antiretroviral drugs. Therefore, it is critical to...

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PMID: 12805437
DOI: 10.1128/jvi.77.13.7383-7392.2003

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