Contrasting genetic burden for bipolar disorder: Early onset versus late onset in an older adult bipolar disorder sample.

doi:10.1016/j.euroneuro.2024.12.001

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Contrasting genetic burden for bipolar disorder: Early onset versus late onset in an older adult bipolar disorder sample.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Mar 2025

Montejo Laura, Sole Brisa, Fico Giovanna, Kalman Janos L, Budde Monika, Heilbronner Urs, Oliva Vincenzo, De Prisco Michele, Martin-Parra Sara, Ruiz Andrea, Martinez-Aran Anabel, Adorjan Kristina, Falkai Peter, Heilbronner Maria, Kohshour Mojtaba Oraki, Reich-Erkelenz Daniela, Schaupp Sabrina K, Schulte Eva C, Senner Fanny, Vogl Thomas, Anghelescu Ion-George, Arolt Volker, Baune Bernhard T, Dannlowski Udo, Dietrich Detlef E, Fallgatter Andreas J, Figge Christian, Juckel Georg, Konrad Carsten, Reimer Jens, Reininghaus Eva Z, Schmauß Max, Wiltfang Jens, Zimmermann Jörg, Vieta Eduard, Papiol Sergi, Schulze Thomas G, Torrent Carla

Abstract excerpt

Older Adults with Bipolar Disorder (OABD) represent a heterogeneous group, including those with early and late onset of the disorder. Recent evidence shows both groups have distinct clinical, cognitive, and medical features, tied to different neurobiological profiles. This study explored the link between polygenic risk scores (PRS) for bipolar disorder (PRS-BD), schizophrenia (PRS-SCZ), and major depressive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Age of Onset

Share to Aged

Share to Bipolar Disorder

Share to Genetic Predisposition to Disease

Share to Major Depressive Disorder

Share to Multifactorial Inheritance

Share to Polymorphism, Single Nucleotide

Share to Schizophrenia

Source

Open in PubMed

Identifiers

PMID: 39718074
DOI: 10.1016/j.euroneuro.2024.12.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contrasting genetic burden for bipolar disorder: Early onset versus late onset in an older adult bipolar disorder sample.PMID 39718074Read ↗

Characterization of Age and Polarity at Onset in Bipolar DisorderSemantic proximity Read ↗

Advancing the Prediction of Factors associated with Bipolar Disorder Risk: Utilizing Early Recognition Tools and Polygenic Risk ScoresSemantic proximity Read ↗

Polygenic risk scores in bipolar disorder subgroups.Semantic proximity Read ↗

Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study.Semantic proximity Read ↗

Characterisation of age and polarity at onset in bipolar disorderSemantic proximity Read ↗

Genetic Risk Score Analysis in Early-Onset Bipolar Disorder.Semantic proximity Read ↗

Dissecting clinical heterogeneity of bipolar disorder using multiple polygenic risk scoresSemantic proximity Read ↗

Age-at-onset in bipolar-I disorder: Mixture analysis of 1369 cases identifies three distinct clinical sub-groupsSemantic proximity Read ↗

Adverse Psychosocial Trajectory in Bipolar Disorder: Novel Genetic Links to ADHD and AnxietySemantic proximity Read ↗

Genetics of bipolar disorder: insights into its complex architecture and biology from common and rare variants.Semantic proximity Read ↗

Key subphenotypes of bipolar disorder are differentially associated with polygenic liabilities for bipolar disorder, schizophrenia, and major depressive disorder.Semantic proximity Read ↗

Clinical, genetic, and brain imaging predictors of risk for bipolar disorder in high-risk individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.