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Article

Minichromosome maintenance (MCM) protein 4 as a marker for proliferation and its clinical and clinicopathological significance in non-small cell lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 May 2011

Kikuchi Junko, Kinoshita Ichiro, Shimizu Yasushi, Kikuchi Eiki, Takeda Kayoko, Aburatani Hiroyuki, Oizumi Satoshi, Konishi Jun, Kaga Kichizo, Matsuno Yoshihiro, Birrer Michael J, Nishimura Masaharu, Dosaka-Akita Hirotoshi

Abstract excerpt

BACKGROUND: Minichromosome maintenance (MCM) proteins 2-7 form a complex essential for the initiation of DNA replication. In the process to screen expression changes related to growth suppression of non-small cell lung cancer (NSCLC) cells by a cJun dominant-negative mutant, we found that reduced expression of MCM4 was correlated with this growth suppression. METHOD: We determined the relevance of MCM4 in...

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Identifiers

PMID: 20884074
DOI: 10.1016/j.lungcan.2010.08.020

Genes

MCM4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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