Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MCM proteins as diagnostic and prognostic tumor markers in the clinical setting.

1 Mar 2010

Abstract excerpt

Minichromosome maintenance (MCM) proteins are essential for the process of DNA replication, functioning as license components for the S-phase of cell-cycle initiation and further exerting weak helicase activity to unwind DNA from its supercoiled state at replication forks. The requirement for MCM proteins in cycling cells and their absence in quiescent ones supports evidence for their potential clinical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to DNA Repair Mechanisms
Share to Microtubule and mitosis dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20054807
DOI: 10.14670/hh-25.351

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MCM proteins as diagnostic and prognostic tumor markers in the clinical setting.PMID 20054807Read ↗

Pan-Cancer Multi-Omics Analysis of Minichromosome Maintenance Proteins (MCMs) Expression in Human CancersSemantic proximity Read ↗

MCM family in gastrointestinal cancer and other malignancies: From functional characterization to clinical implicationSemantic proximity Read ↗

MCM2 in human cancer: functions, mechanisms, and clinical significanceSemantic proximity Read ↗

The MCM Complex: Its Role in DNA Replication and Implications for Cancer TherapySemantic proximity Read ↗

Multi-omics pan-cancer analyses identify MCM4 as a promising prognostic and diagnostic biomarkerSemantic proximity Read ↗

Elevated expression of minichromosome maintenance 3 indicates poor outcomes and promotes G1/S cell cycle progression, proliferation, migration and invasion in colorectal cancerSemantic proximity Read ↗

Bioinformatics analysis of the transcriptional expression of minichromosome maintenance proteins as potential indicators of survival in patients with cervical cancerSemantic proximity Read ↗

Multi-Omics Analysis of MCM2 as a Promising Biomarker in Pan-CancerSemantic proximity Read ↗

Potential Prospective Biomarkers for Non-small Cell Lung Cancer: Mini-Chromosome Maintenance ProteinsSemantic proximity Read ↗

Comprehensive Analysis of the Expression and Prognosis for MCMs in Human Gastric Cancer.Semantic proximity Read ↗

Expression and Prognostic Value of MCM Family Genes in OsteosarcomaSemantic proximity Read ↗

DNA Replication Licensing Protein MCM10 Promotes Tumor Progression and Is a Novel Prognostic Biomarker and Potential Therapeutic Target in Breast CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.