Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RNF125‑mediated ubiquitination of MCM6 regulates the proliferation of human liver hepatocellular carcinoma cells

17 Jan 2024

Abstract excerpt

Hepatocellular carcinoma (HCC) is the third leading cause of cancer-associated mortality worldwide. Minichromosome maintenance proteins (MCMs), particularly MCM2-7, are upregulated in various cancers, including HCC. The aim of the present study was to investigate the role of MCM2-7 in human liver HCC (LIHC) and the regulation of the protein homeostasis of MCM6 by a specific E3 ligase. Bioinformatics analyses...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ferroptosis and cancer prognosis
Share to RNA modifications and cancer
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38298426
DOI: 10.3892/ol.2024.14238

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RNF125‑mediated ubiquitination of MCM6 regulates the proliferation of human liver hepatocellular carcinoma cellsPMID 38298426Read ↗

MCM7 promotes cancer progression through cyclin D1-dependent signaling and serves as a prognostic marker for patients with hepatocellular carcinomaSemantic proximity Read ↗

The impact of MCM6 on hepatocellular carcinoma in a Southern Chinese Zhuang populationSemantic proximity Read ↗

Expression and prognosis of microliposome maintenance proteins family in liver cancerSemantic proximity Read ↗

MCM family in gastrointestinal cancer and other malignancies: From functional characterization to clinical implicationSemantic proximity Read ↗

MCM6 indicates adverse tumor features and poor outcomes and promotes G1/S cell cycle progression in neuroblastomaSemantic proximity Read ↗

MCM6 indicates adverse tumor features and poor outcomes and promotes G1/S cell cycle progression in neuroblastomaSemantic proximity Read ↗

Comprehensive Analysis of the Expression and Prognosis for MCMs in Human Gastric Cancer.Semantic proximity Read ↗

Transcriptional Expression of Minichromosome Maintenance 10 as an Independent Negative Predictor of Survival in Hepatocellular CarcinomaSemantic proximity Read ↗

MCM2-7 in Clear Cell Renal Cell Carcinoma: MCM7 Promotes Tumor Cell ProliferationSemantic proximity Read ↗

Elevated expression of minichromosome maintenance 3 indicates poor outcomes and promotes G1/S cell cycle progression, proliferation, migration and invasion in colorectal cancerSemantic proximity Read ↗

Identification of MCM4 as a Prognostic Marker of Hepatocellular CarcinomaSemantic proximity Read ↗

Pan-Cancer Multi-Omics Analysis of Minichromosome Maintenance Proteins (MCMs) Expression in Human CancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.