Article
Genetic pathways regulating glutamate levels in retinal Müller cells.
Neurochemical research - 1 Apr 2011
Jablonski Monica M, Freeman Natalie E, Orr William E, Templeton Justin P, Lu Lu, Williams Robert W, Geisert Eldon E
Abstract excerpt
Müller cells serve many functions including the regulation of extracellular glutamate levels. The product of two genes, Slc1a3 [aka solute carrier family 1 (glial high affinity glutamate transporter), member 3] and Glul (aka glutamine synthetase) are the primary role players that transport glutamate into the Müller cell and convert it into glutamine. In this study, we sought to identify the genetic regulation of...
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