Article
Systemic Lupus Erythematosus in Children and Young People.
Current rheumatology reports - 10 Feb 2021
Charras A, Smith E, Hedrich C M
Abstract excerpt
PURPOSE OF REVIEW: Juvenile-onset systemic lupus erythematosus ((j)SLE) is an autoimmune/inflammatory disease that results in significant damage and disability. When compared to patients with disease onset in adulthood, jSLE patients exhibit increased disease activity, damage and require more aggressive treatments. This manuscript summarises age-specific pathogenic mechanisms and underscores the need for age...
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