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Article

Suppression of p21 by c-Myc through members of miR-17 family at the post-transcriptional level

22 Sept 2010

Abstract excerpt

The miR-17 family, composed of miR-17-5p, miR-20a/b, miR-106a/b and miR-93, has been demonstrated to take part in critical pathways that regulate cellular life and death decisions during normal development and in malignancy. Previous studies have shown that the expression of miR-17 family members has close relationship with the expression of c-Myc. Another study has reported p21 is a direct target of miR-17...

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PMID: 20878079
DOI: 10.3892/ijo_00000783

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