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Article

Increased cancer risks for relatives of very early-onset breast cancer cases with and without BRCA1 and BRCA2 mutations.

British journal of cancer - 28 Sept 2010

Dite G S, Whittemore A S, Knight J A, John E M, Milne R L, Andrulis I L, Southey M C, McCredie M R E, Giles G G, Miron A, Phipps A I, West D W, Hopper J L

Abstract excerpt

BACKGROUND: Little is known regarding cancer risks for relatives of women with very early-onset breast cancer. METHODS: We studied 2208 parents and siblings of 504 unselected population-based Caucasian women with breast cancer diagnosed before age 35 years (103 from USA, 124 from Canada and 277 from Australia), 41 known to carry a mutation (24 in BRCA1, 16 in BRCA2 and one in both genes). Cancer-specific...

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Age of Onset
Family
Family Health
Genes, BRCA1
Genes, BRCA2

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Identifiers

PMID: 20877337
DOI: 10.1038/sj.bjc.6605876
PMCID: PMC2965877

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BRCA1
BRCA2

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