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Article

Prevalence of BRCA1 and BRCA2 gene mutations in patients with early-onset breast cancer.

Journal of the National Cancer Institute - 2 Jun 1999

Peto J, Collins N, Barfoot R, Seal S, Warren W, Rahman N, Easton D F, Evans C, Deacon J, Stratton M R

Abstract excerpt

BACKGROUND: Mutations in the BRCA1 and BRCA2 genes are found in most families with cases of both breast and ovarian cancer or with many cases of early-onset breast cancer. However, in an outbred population, the prevalence of BRCA1 and BRCA2 mutations in patients with breast cancer who were unselected for a family history of this disease has not been determined. METHODS: Mutations in the BRCA1 and BRCA2 genes were...

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Source

Identifiers

PMID: 10359546
DOI: 10.1093/jnci/91.11.943

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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