Article
H2B- and H3-specific histone deacetylases are required for DNA methylation in Neurospora crassa.
Genetics - 1 Dec 2010
Smith Kristina M, Dobosy Joseph R, Reifsnyder Jennifer E, Rountree Michael R, Anderson D C, Green George R, Selker Eric U
Abstract excerpt
Neurospora crassa utilizes DNA methylation to inhibit transcription of heterochromatin. DNA methylation is controlled by the histone methyltransferase DIM-5, which trimethylates histone H3 lysine 9, leading to recruitment of the DNA methyltransferase DIM-2. Previous work demonstrated that the his...
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