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Article

Mechanical activation of β-catenin regulates phenotype in adult murine marrow-derived mesenchymal stem cells.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Nov 2010

Case Natasha, Xie Zhihui, Sen Buer, Styner Maya, Zou Minxu, O'Conor Chris, Horowitz Mark, Rubin Janet

Abstract excerpt

Regulation of skeletal remodeling appears to influence the differentiation of multipotent mesenchymal stem cells (MSC) resident in the bone marrow. As murine marrow cultures are contaminated with hematopoietic cells, they are problematic for studying direct effects of mechanical input. Here we use a modified technique to isolate marrow-derived MSC (mdMSC) from adult mice, yielding a population able to...

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Identifiers

PMID: 20872592
DOI: 10.1002/jor.21156
PMCID: PMC3046385

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MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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