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Article

Shaking culture enhances chondrogenic differentiation of mouse induced pluripotent stem cell constructs.

Scientific reports - 14 Sept 2020

Limraksasin Phoonsuk, Kosaka Yukihiro, Zhang Maolin, Horie Naohiro, Kondo Takeru, Okawa Hiroko, Yamada Masahiro, Egusa Hiroshi

Abstract excerpt

Mechanical loading on articular cartilage induces various mechanical stresses and strains. In vitro hydrodynamic forces such as compression, shear and tension impact various cellular properties including chondrogenic differentiation, leading us to hypothesize that shaking culture might affect the chondrogenic induction of induced pluripotent stem cell (iPSC) constructs. Three-dimensional mouse iPSC constructs...

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Identifiers

PMID: 32929163
DOI: 10.1038/s41598-020-72038-y
PMCID: PMC7490351

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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